XU Nan, ZHANG Qi, CAO Yue, et al. Chemical Constituents from and their Scavenging Activities for DPPH Radical[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 162-166.
XU Nan, ZHANG Qi, CAO Yue, et al. Chemical Constituents from and their Scavenging Activities for DPPH Radical[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 162-166.DOI:
Objective:Study on the chemical constituents from Cibotium barometz and their scavenging activities for 2
2-diphenyl-2-picrylhydrazyl (DPPH) radical. Method: The chemical constituent from70% alcohol extract of C. barometz was isolated on chromatograph of silica gel and sephadex LH-20 and HPLC
their structure were elucidated on the basis of spectra data and the compounds were tested for their scavenging activities on DPPH radical. Result: Ten compounds were purified and their structure were identified as 1-O-caffeyl-D-glucopyranose ( 1 )
6-O-caffeyl-D-glucopyranose ( 2 )
3-O-caffeyl-D-glucopyranose ( 3 )
3-hydroxymethyl-2(5H)-furanone ( 4 )
β-miroside( 5 )
cibotiumbaroside A( 6 )
protocatechuic acid ( 7 )
glucose ( 8 )
mannose ( 9 )
Corchoionoside C ( 10 )
kojic acid ( 11 ). Three isolated compounds showed strong scavenging activities on DPPH radical. Conclusion: Compound 1-5 were isolated for the first time from C. barometz. among of them
compound 1
compound 3 and compound 6 showed significant antioxidant activity
and the scavenging activity of compound 1 was similar to that of Vit C.