Objective:To optimize extraction technology of quercitrin from bark of Carya cathayensis

and establish its content determination method. Method: Ethanol reflux extraction method was conducted

extraction solution was absorbed by polyamide to remove dopant

then condensed

crystallized and recrystallized to obtain pure product. After identification by NMR

the content of quercitrin was determined by HPLC.Orthogonal test was used to investigate influence of the concentration of ethanol

extraction time and extraction times on yield of quercitrin. Result: NMR verified product as quercitrin

HPLC showed that quercitrin had a good linear relationship in the range of 4.8-91.2 mg·L-1

the content of quercitrin from bark of C. cathayensis was up to 8.37%.Optimum extraction technology was:reflux extracted 2 times with 10 times the amount of 60% ethanol

1 h per time

extraction rate of quercitrin 90%. Conclusion: Established content determination method of quercitrin from C. cathayensis was accurate and simple

optimized extraction technology was stable and feasible.