PEI Qiang, SANG Wen-feng, ZHAO Xi-de. Clinical Study of Guizhi Fuling Decoction and Huanglian Jiedu Decoction in Treatment of Unstable Angina[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 286-289.
PEI Qiang, SANG Wen-feng, ZHAO Xi-de. Clinical Study of Guizhi Fuling Decoction and Huanglian Jiedu Decoction in Treatment of Unstable Angina[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 286-289.DOI:
共3周。观察两组治疗前后临床症状、24 h动态心电图、血脂及血清高敏C-反应蛋白(high-sensitivity C-reactive protein
hs-CRP)变化。 结果: 治疗后两组各指标较治疗前均明显改善(P<0.05)
治疗组能进一步降低心绞痛发作频率、心肌缺血次数、缺血持续最长时间、心肌缺血总时间及hs-CRP水平(P<0.05);升高高密度脂蛋白胆固醇 (high density lipoprotein cholesterol
HDL-C)(P<0.05)。 结论: 桂枝茯苓汤合黄连解毒汤对UA有确切疗效。
Abstract
Objective:To observe the therapeutic effects of Guizhi Fuling decoction(GFD) and Huanglian Jiedu decoction(HJD) on patients with unstable angina(UA). Method: Seventy-two UA patients were randomly assigned to the treatment group(36 cases) and the control(36 cases). All were treated by the regular UA treatment
but to patients in the treatment group
GFD and HJD was given additionally. The course of treatment was three weeks. Before and after the treatments
changes of clinical symptoms
24-hour ambulatory electrocardiogram(AECG)
blood lipids and serum levels of high-sensitivity C-reactive protein(hs-CRP) were observed. Result: Compared with before treatment
obvious improvement of clinical symptom and experiment index was obtained in two groups. After treatment
the frequency of angina attacks
myocardial ischemia times in 24 h
the longest duration of a single myocardial ischemia
the total duration of myocardial ischemia in 24 h and hs-CRP were reduced and high density lipoprotein cholesterol(HDL-C) was increased further in the treatment group(P<0.05). Conclusion: GFD and HJD showing definite effects on UA.