Objective: To study the clinical curative effect of Bozi Ziyin Runchang decoction (BZRD) for treatment chronic functional constipation (CFC) and the influence on the colon transmission function. Method: One hundred and sixteen cases of CFC were randomly divided into treatment group and control group

59 cases and 57 cases respectively.The treatment group was given BZRD

1 agent/daily

the control group was given Maren Runchang soft capsule

8 capsules

bid. Period of treatment was 4 weeks. Symptom of defecation difficult

Bristol score

defecation time

defecation frequency and abdominal distension

and begin colon transmission test were observed. Result: After treatment

the treatment group's symptom defecation difficult was significantly lower than that in control group (P<0.01); after the treatment and 4 weeks after treatment

whole colon transmission time in the treatment group was less than that in control group (P<0.01); after treatment

the treatment group total effectiveness was 93.22%

which is higher than that of 77.19% in control group (P<0.05). After treatment

the two groups of the recurrence rate difference was not obvious. Conclusion: BZRD for treatment of CFC has significant clinical curative effect

good safety

promising clinical application.