Objective: To observe the clinical effects of supplementing Qingnao Jiangya tablets for treatment of essential hypertension (yin deficiency and yang excess). Method: One hundred and twenty-four patients with essential hypertension were equally and randomly divided into treatment group and control group. Both two groups were given conventional non-drug therapy. The control group was given captopril orally 25 mg tid

and the treatment group was supplemented by Qingnao Jiangya tablets 5 tablets tid. Course of treatment were 8 weeks. Systolic and diastolic blood pressure (SBP

DBP) before treatment

4 weeks and 8 weeks after treatment were monitored. Inteleukin-6

8(IL-6

IL-8) and high-sensitivity C protein (hs-CRP) before and after treatment were detected. Result: SBP and DBP in treatment group at 4 weeks and 8 weeks after treatment were lower than those in the control group (P<0.05

P<0.01). IL-6

IL-8 and hs-CRP of both groups were lower than those before treatment

and the treatment group were lower than the control group (P<0.01). In the treatment group

the symptom curative effect and blood pressure control were better than those in the control group (P<0.01). Conclusion: The Qingnao Jiangya tablets have good clinical effects for treating essential hypertension (yin deficiency and yang excess type)

besides

it can also regulate the inflammatory factors

protect the vascular endothelium.