HU Zheng-fang, LI Chu-xi, JIA Shu-tian, et al. Optimization of Extraction Technology for Lovastatin from by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 53-55.
HU Zheng-fang, LI Chu-xi, JIA Shu-tian, et al. Optimization of Extraction Technology for Lovastatin from by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(24): 53-55.DOI:
Objective:To optimize extraction technology of lovastatin from Monascus purpureus. Method: With composite score of yield of dry extract and transfer rate of lovastatin as index
taking extraction times
extraction time
the concentration and amount of ethanol as factors
extraction technology of lovastatin from M. purpureus was optimized by L9 (34) orthogonal test. Result: Optimum extraction technology was as follows:reflux extracted 2 times with 6 times the amount of 95% ethanol
0.5 h per time. Conclusion: This optimized extraction technology was feasible
stable and reasonable with high yield of lovastatin.