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纸质出版日期:2013
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牛贵义. 利胆排石汤联合纤维十二指肠镜治疗胆总管结石40例[J]. 中国实验方剂学杂志, 2013,19(2):322-324.
NIU Gui-yi. Lidan Paishi Decoction Combined with Fiber Endoscopic Treatment in 40 Cases with Common Bile Duct Stones[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(2): 322-324.
目的: 观察纤维十二指肠镜联合利胆排石汤治疗胆总管结石的临床疗效。 方法: 将80例胆总管结石患者随机分为观察组、对照组各40例。对照组给予纤维十二指肠镜治疗
观察组在对照组治疗的基础上给予利胆排石汤治疗
手术前后1周内每日1剂
水煎服。观察比较两组患者发热、黄疸、腹痛等为临床症状积分的改善情况及治疗前和治疗后3个月时门冬氨酸氨基转移酶(AST)、丙氨酸氨基转移酶(ALT)、淀粉酶(AMY)、总胆红素(TBil)水平。 结果: 黄疸、发热、恶心呕吐、腹痛等症状积分治疗后观察组分别为(0.75±0.12)
(0.87±0.15)
(0.81±0.18)
(0.54±0.26)分
对照组分别为(1.57±0.22)
(1.43±0.37)
(1.47±0.24)
(1.74±0.26)分
两组均明显好转 (P<0.05)
观察组优于对照组(P<0.05)。 TBil
AMY
ALT
AST治疗后观察组分别为(12.54±2.25)μmol·L-1
(48.43±18.87)
(33.54±6.42)
(33.34±4.25)U·L-1
对照组分别为(19.75±6.25)μmol·L-1
(84.53±13.57)U·L-1
(34.71±6.24)U·L-1
(33.94±5.16)U·L-1
两组均明显好转 (P<0.05)
TBil
AMY下降
观察组优于对照组(P<0.05)。 结论: 纤维十二指肠镜联合利胆排石汤治疗胆总管结石可改善临床症状及血清TBil
AMY水平。
Objective: To observe clinical curative effect of fiber duodenoscopy combined Lidan Paishi decoction (LPD) in treatment of common bile duct stones. Method: Eighty cases of common bile duct stones were randomly divided into observation group and control group
40 cases in each. The 2 groups were given anti-infective
maintenance of water
electrolyte
acid-base balance as foundation treatment. The control group was given the fibers treated with endoscopy
based on the control treatment the observation group was given LPD treatment
before and after 1 week of operation daily. Two groups were observed in patients with fever
jaundice
abdominal pain and other clinical symptoms integral improvement and before treatment and after treatment at 3 months total bilirubin (TBil)
amylase (AMY)
alanine aminotransferase (ALT)
aspartate aminotransferase (AST) levels. Result: Jaundice
fever
nausea and vomiting
abdominal pain and other symptoms integral in the observation group after treatment group were (0.75±0.12)
(0.87±0.15)
(0.81±0.18)
(0.54±0.26)
the control group were (1.57±0.22)
(1.43±0.37)
(1.47±0.24)
(1.74±0.26)
the two group were significantly improved (P<0.05)
and the TBil and Amy of observation group were better than that of the control group (P<0.05). TBil
AMY
ALT
AST index after treatment in observation group were (12.54±2.25)μmol·L-1
(48.43±18.87)
(33.54±6.42)
(33.34±4.25) U· L-1
control group were (19.75±6.25)μmol·L-1
(84.53±13.57)
(34.71±6.24)
(33.94±5.16) U· L-1
two groups were significantly improved (P<0.05)
and the TBil and Amg of the observation group were better than that of the control group(P<0.05). Conclusion: Fiber duodenoscopy combined LPD for the treatment of common bile duct stones can improve clinical symptoms and serum TBil
AMY levels.
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