This paper is aimed to summarize the anti-cancer effects and mechanism of Juglans mandshurica. Nearly 40 documents

which were contributed by both domestic and foreign researchers

where found in the databasses sush as cqvip

sciFinder and other ones. The anti-tumor effect of the J. mandshurica can be summarized to the following 6 aspects: affecting cell cycle

inhibiting of DNA topoisomerase

inducing apoptosis of tumor cells

improving the immune system

damaging the mitochondrial structure

changing the structure and biochemical of cell membrane. J. mandshurica. has an bright future as a anti-cancer drug and it is worthy further studies to obtain a more efficient product with lower toxicity.