Objective:To observe the effect of Kang'ai injection combined with chemotherapy in the treatment of malignant tumor for the clinical curative effect. Method:Eighty cases of malignant tumor were randomly divided into observation group and control group with 40 cases in each group. The two groups were given pemetrexed and cisplatin combined chemotherapy. The observation group was additionally given Kang'ai injection (5% glucose injection 250 mL+Kang'ai injection 50 mL

intravenous infusion

daily) for 30 d. Result:The 1 year survival rate in observation group was 65%

while in control group was 45%

two groups had significant difference (P<0.05). The 3 year survival rate in observation group was 37.50%

while in control group was 25%

two groups had significant difference (P<0.05). The scores for physical health

mental health

social relations

environmental factors after treatment in the observation group were (25.7± 6.2)

(23.3 ±3.7)

(23.7 ±6.4) and (22.4 ±4.6)

while in the control group were (15.7± 6.2)

(14.3 ±3.7)

(14.7 ±6.4) and (17.4 ±4.6)

the observation group was better than the control group (P<0.05). Though two groups were significantly improved (P<0.05). After treatment

IL-6

TNF-α in observation group were (445.74± 96.22)

(393.35 ±83.57) ng·L-1

while those in control group were (385.44± 79.26)

(358.33 ±73.82) ng·L-1

two groups were significantly improved (P<0.05) and the observation group was better than the control group (P<0.05). After treatment CD3+

CD4+

CD8+and CD4+/CD8+in the observation group were(55.54±8.25) %

(38.43 ±8.87) %

(23.54 ±6.42) % and (1.34±0.25)

those in the control group were (49.35±10.25)%

(34.35±8.32)%

(28.52±7.45) %

and (1.20±0.16). Two groups were significantly improved (P<0.05)

while the observation group was better than the control group (P<0.05). Conclusion:Kang'ai injection combined with chemotherapy in the treatment of malignant tumor shows significant curative effect. The therapy can prolong the survival of patients

improve the quality of life.