Objective:To investigate the impact of Shenfu Qiangxin pills on cardiac function

brain natriuretic peptide and inflammatory factor levels on patients with chronic heart failure (CHF). Method: Seventy-six cases of CHF were equally divided into treatment group (39 cases) and control group (37 cases). The control group was given conventional western treatment

the treatment group was used Shenfu Qiangxin pills 6 g

tid for 8 weeks on the basis of the control group. Cardiac function

left ventricular function

traditional Chinese medicine(TCM) syndrome score

N-terminus of the original brain natriuretic peptide(NT-proBNP)

C-reactive protein(CRP)

tumor necrosis factor(TNF-α)and interleukin-6 (IL-6) in the two groups were observed before and after the intervention. Result: The treatment group was better than the control group on the aspects of decreasing left ventricular end diastolic diameter (LVEDD) and increasing ventricular ejection fraction (LVEF)(P<0.01). The TCM syndrome scores

plasma NT-proBNP level

plasma CRP

TNF-α and IL-6 levels in the treatment group were lower than those in the control group(P<0.01). Conclusion: Shenfu Qiangxin pills can significantly improve cardiac function in patients with CHF

reduce TCM syndrome score and reduce the level of plasma NT-proBNP. Its mechanism may be related to the inhibition of inflammatory cytokines to reduce the inflammatory response.