Objective:To observe the clinical efficacy of Revised Maziren Pill (RMP) for the treatment of intestinal constipation caused by opium alike. Method: Sixty-six subjects with intestinal constipation caused by opium alike were randomly divided into two groups

33 patients in the treatment group administered with RMP

33 in the control group administered with aetulose liquo. Then the clinical symptom scores

quality of life

defecation interval

the time of each defecation

stool form

the dimensions of the difficulty for the defecation and so on were evaluated before treating and after 2 weeks of treating. Result: Treatment group showed improved clinical symptom and quality of life

and relieved difficulty. Treatment could shorten interval

the first time of defecation and the time of each defecation

relieve the difficulty for the defecation

and so the effectiveness in the treatment group was better than that in control group (P<0.05). Conclusion: RMP can release constipation induced by opium alike and pain effectively

also can improve quality of life.