Objective:To investigate the clinical efficacy of amlodipine and atorvastatin combined with Shuxin Jianzhi tables on treatment of hypertension with dyslipidemia. Method: One hundred and ten hypertensive patients with abnormal lipid were randomly divided into two groups

58 in the control group and 57 in the treatment group

All patients were experienced a two-week washout period

the control group was given with Shuxin Jianzhi tables

4 tablets/time

tid; the treatment group was given amlodipine and atorvastatin(Duodayi

5 mg∶10 mg)once daily for 24 weeks. Changes in blood lipids

blood pressure and cardiovascular adverse event before and after treatment were observed. Result: The blood pressure in the treatment group was more efficient compared with that in the control group (P<0.05). The level of total cholesterol (TC)

triglyceride (TG)

low density lipoprotein cholesterol(LDL-C) and high density lipoprotein cholesterol(HDL-C) were significant improved in the two groups

the treatment group's improvement was better than that in the control group(P<0.05); The adverse event rate in the treatment group was 8.77%

and that in the control group was 18.86%. Conclusion: Amlodipine and atorvastatin combined with Shuxin Jianzhi tablets was an effective and safe medication program. It can effectively control blood pressure with hypertension and dyslipidemia

can significantly improve the blood lipid levels.