Objective: To investigate the effect of Tanreqing-injection on lymphocytes in patients for squamous cell carcinoma of lung after radiotherapy. Method: Seventy cases with squamous cell carcinoma of lung treated by radiotherapy were divided equally into two groups: control group and test group treated by Tanreqing-injection

at the same time both groups were treated by radiotherapy. The patients of both groups were subjected to relevant laboratory examination to observe the routine blood indexes and simultaneously peripheral blood lymphocytes were detected by flow cytometry(FCM)before or after medication.The ordinary silver staining technology was to measure the relative content(I.S) of AgNORs in lymphocytes. The incidence of radiation esophagitis and radiation pneumonia for the both groups was also investigated. Result: After radiotherapy

the routine blood indexes of the both groups reduced

but Hb

WBC and lymphocyte count inTanreqing-injection group were obviously higher than control group(P<0.05). The incidence of radiation esophagitis and radiation pneumonia in Tanreqing group were obviously lower than control group (P<0.05).Meanwhile the improvement of peripheral-blood lymphocytes subset and I.S% value of test group patients was observed more notablely powerful than control group's(P<0.01). Conclusion: Tanreqing-injection has certain immunoregulation action on lymphocytes in patients with squamous cell carcinoma of lung after radiotherapy. Tanreqing-injection also possess prophylaxis prevention action on radiation esophagitis and radiation pneumonia caused by radiotherapy.