Objective: To investigate film-forming property of main film-forming materials in water and ethanol extraction liquid of Lycopus lucidus

and to provide a reference for selection and application of film-forming materials from Chinese medicine spray including L. lucidus. Method: According to solubility of film-forming materials

polyvinyl pyrrolidone (PVP)

polyvinyl alcohol (PVA)

ethyl cellulose (EC) and methyl cellulose (MC) were used to investigate property of film-forming materials in different extraction solution of L. lucidus by picture analyzing membrane structure with microscope and image capture software. Result: PVP-K30 and PVP-K90 had a goof film-forming ability with a fine texture

smooth and neat membrane.PVA-1788 would form membrane in water and ethanol extraction liquid of L. lucidusin

but membrane surface was uneven and rough with a small amount of particles.MC-400 and MC-1500 could from a layer of thick

smooth

dense membrane with excellent film-forming property in different extraction solution of L. lucidusin

but EC-9-11 and EC-6-9 had poor film-forming properties in 80% ethanol extraction liquid of L. lucidusin

membrane structure was unobvious

film-forming property of MC decreased with increasing ethanol concentration from extraction liquid of L. lucidusin. Conclusion: Polarity of solvent showed relationship with selecting of film-forming materials

PVP-K30 was optimum film-forming material for Chinese medicine spray and film agent including L. lucidusin.