JIANG Gui-ping. Effect of Huoxue Tiaozhi Decoction on Hemorheological Parameters and Blood Lipids in Coronary Heart Disease Patients after PCI[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 281-283.
JIANG Gui-ping. Effect of Huoxue Tiaozhi Decoction on Hemorheological Parameters and Blood Lipids in Coronary Heart Disease Patients after PCI[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(18): 281-283.DOI:
Objective: To observe effect of Huoxue Tiaozhi Decoction on blood rheology of blood lipid regulation in coronary heart disease patients after percutaneous coronary intervention (PCI). Method: With incorporated into standard in 60 cases of PCI patients were randomly divided into observation group and control group
40 cases in each. Two groups of patients after PCI were given aspirin enteric-coated tablets 100 mg
bid
simvastatin tablet:(40 mg
bid).Observation group was added with Huoxue Tiaozhi Decoction
boiling water service
250 mL/bid. The 2 groups were treated for 1 month as 1 course
2 courses as the treatment.Hemorheology and serum total cholesterol (TC)
triglyceride (TG)
low density lipoprotein (LDL-C)
high density lipoprotein (HDL-C) were observed. Result: The blood high
medium
low shear viscosity
plasma viscosity
hematocrit in treatment group were (3.52±0.62)
(4.33±0.54)
(7.18±1.55)
(1.32±0.14) mPa · s
(34.43±5.54)%;the control group were (3.72±0.58)
(4.52±0.64)
(7.41±1.23)
(1.41± 0.15) mPa · s
(36.78±5.68)%. The two groups after treatment were significantly improved (P<0.05)
and the treat ment group was better than the control group (P<0.05). TC
TG
LDL-C
HDL-C indexes after treatment in treatment group were (3.61±0.41)
(2.31±0.52)
(3.75±0.38)
(1.95±0.26) mmol · L-1
those in the control group were (3.72±0.58)
(4.52±0.64)
(7.41±1.23)
(1.41±0.15) mmol · L-1. The two groups after treatment were significantly improved (P<0.05)
and the treatment group was better than the control group (P<0.05). Conclusion: Huoxue Tiaozhi decoction used in coronary heart disease patients after PCI can improve hemorheological paramenters