Objective: To optimize extraction technology of Zhongfeng Huoxin soft capsule. Method: Volatile oil from Zhongfeng Huoxin prescription was extracted by steam distillation method

with yield of volatile oil as index

orthogonal test was adopted to optimize extraction technology with the amount of water

soaking time and distillation time as factors;With the content of puerarin as index

the amount of water

boiling time and extraction times were selected as factors

extraction technology of Zhongfeng Huoxin soft capsule was optimized by orthogonal test. Result: The best extraction technology of volatile oil was as follows:without soaking

distilled 7 h with 6 times the amount of water;optimum water extraction process of Zhongfeng Huoxin soft capsule was as follows:extracted 3 times with 10 times the amount of water

1.0 h each time. Conclusion: This optimized extraction technology was stable and reliable

it could be extended to large-scale production application of Zhongfeng Huoxin soft capsule.