Objective: To establish the methods of quality control for Wangbiwan capsules. Method: Cortex Cinnamomum

Ramulus Cinnamomi

Radix Paeoniae Alba

Radix Paeoniae Bubra and Radix Saposhnikoviae were identified by TLC; and the content of osthole

cinnamaldehyde and cinnamic acid in Wangbiwan capsules was determined by HPLC. Result: TLC spots developed were fairly clear and the blank tests showed no interference for Radix Paeoniae Alba

Paeonia lactiflora Pall and Radix Saposhnikoviae

but similar component in TLC were found for Cinnamomum cassia and Ramulus Cinnamomi. The linear ranges of osthole

cinnamaldehyde and cinnamic acid were 1.0-200

5.0 -100.0 and 0.50-15.0 mg·L-1respectively with average recovery of 98.16%-101.6%

RSD of 1.9%-3.0%. Conclusion: The TLC and HPLC methods were smiple

accurate and fast

which could be used effectively for the quality control of Wangbiwan capsules.