正交试验法优选萸丹胶囊的水提工艺

陈威; 侯伟源; 刘坚初; 叶炳皇; 贺倩; 张军; 林吉

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正交试验法优选萸丹胶囊的水提工艺

更新时间：2024-01-04

- 正交试验法优选萸丹胶囊的水提工艺
- Optimization of Water Extraction Technology of Yudan Capsule by Orthogonal Test
- 中国实验方剂学杂志 2012年18卷第20期页码：28-30
- 作者机构：
- 作者简介：
- 基金信息：
  
  广东省产学研项目(KCF209112K05);广东省国际合作项目(2011B050300021)
- DOI：
  中图分类号：
- 纸质出版日期：2012
- 稿件说明：
移动端阅览
陈威, 侯伟源, 刘坚初, 等. 正交试验法优选萸丹胶囊的水提工艺[J]. 中国实验方剂学杂志, 2012,18(20):28-30.

CHEN Wei, HOU Wei-yuan, LIU Jian-chu, et al. Optimization of Water Extraction Technology of Yudan Capsule by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 28-30.
陈威, 侯伟源, 刘坚初, 等. 正交试验法优选萸丹胶囊的水提工艺[J]. 中国实验方剂学杂志, 2012,18(20):28-30. DOI：

CHEN Wei, HOU Wei-yuan, LIU Jian-chu, et al. Optimization of Water Extraction Technology of Yudan Capsule by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(20): 28-30. DOI：

摘要

目的: 优选萸丹胶囊的水提工艺。方法: 以马钱苷、丹酚酸B、绿原酸的综合保留率为评价指标

单因素试验考察提取次数;选取加水量、浸泡时间及煎煮时间为考察因素

采用正交试验设计优选萸丹胶囊的水提工艺。结果: 最佳提取工艺为加8倍量水浸泡0.5 h

煎煮1 h

过滤

滤渣加6倍量水煎煮1 h。结论: 该优选工艺稳定、合理

可为萸丹胶囊的生产提供实验依据。

Abstract

Objective:To optimize water extraction technology of Yudan capsule. Method: With comprehensive retention rate of loganin

salvianolic acid B and chlorogenic acid as index

extraction times was optimized by single factor test;the amount of water

soaking time and boiling time were chosen as factors

water extraction technology of Yudan capsule was optimized by orthogonal design. Result: Optimal extraction technology was as follows:soaked 0.5 h with 8 times the amount of water

decocted for 1 h

filtered

residues added 6 folds the amount of water and decocted for 1 h. Conclusion: This optimized extraction technology was stable and reasonable

which provided experimental basis for production of Yudan capsule.

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