Objective:To optimize purification technology of tea-polyphenol from tea stalk by macroporous resin

and provide a reference for secondary development of tea stalk. Method: Static absorption-desorption and dynamic adsorption-desorption was used to select the best one from 9 different type macroporous resin;With the content of tea-polyphenol as index

purification technology parameters of tea polyphenol were optimized by single factor test. Result: LX-18 type resin showed the best purifying profile

its optimum technology conditions were as follows:crude drugs-dry resin weight 1∶1

adsorption rate of 2 mL·min-1

eluted by 10 BV distilled water and 10 BV 50% ethanol;Purity of tea polyphenol was 53.79%. Conclusion: This optimized technology was simple and feasible with good purification effect

so it could provide a reference for development of related products of tea polyphenol.