Objective: To observe the clinical efficacy and safety of radiation intervention combined with traditional Chinese medicine(TCM) in treatment of tubal pregnancy. Method: Sixty-two patients were randomly divided the into control group and research group. The control group was treated with radiation intervention to fallopian tube combined with continuously methotrexate(MTX) infusion. The research group was treated with ectopic pregnancy prescription for 2 weeks based on above mentioned method. The disappeared time of clinical symptoms

the β-human chorionic gonadotropin(β-HCG) level in serum

the changes of lesion size

and the occurrence of side effect before and after the therapeutics were observed. Result: After 2 weeks

the cure rate for research group was 90.3%

and the control group was 74.2%

and there was significant difference(P<0.05). The relative efficacy indexes of research group (such as the disappeared time of clinical symptoms

the recovered time of β-HCG level in serum

and the narrow rate of lesion size) were better than control group. Conclusion: The radiation intervention combined with TCM indicates significantly therapeutic efficacy

it can obviously reduce the cure time and side effects

and there was certain clinical application value.