Objective: To study the chemical components of Qili Qiangxin capsule and to clear its material basis for efficacy. Method: The compounds were isolated from fractions eluted by 50% ethanol and 10% ethanol on sephadex LH-20

MPLC and PHPLC repeatedly. Result: Twelve compounds were isolated and their structures were elucidated on the basis of chemical methods and spectral analysis. They were identified as 5'

7-dihydroxy-3'-methoxyisoflavone (1)

ginsenoside Rb1 (2)

ginsenoside Rf (3)

ginsenoside Re (4)

2'-hydroxy-3'

4'-dimethoxy- isoflavane-7-O-β-D-glucoside (5)

formononetin 7-O-β-D-glucopyranoside (6)

(20R)- ginsenoside Rh1 (7)

8Z-decaene-4

6-diyne-1-O-β-D-glucopyranoside (8)

periplocin (9)

5-hydroxy-2-methoxy-phenmerhylol (10)

adenine riboside (11)

quercetin-3-O-β-D-gluco- pyranosyl-7-O-β-gentiobioside (12). Conclusion: Compounds 1

5-12 are isolated from Qili Qiangxin capsule for the first time and compound 10 is a new natural product.