Objective: To observe the effect of liquefying the necrotic tendons of diabetic foot and promotion of wound healing using the treatment of Huafu Zaisheng. Method: One hundred and seven patients suffering from diabetic foot were randomLy divided into Huafu Zaisheng group(35 cases)

Huafu group(36 cases)

Zaisheng group(36 cases)

then had eroded debridement timely for its wounds. After that

different drugs were used for the wound dressing and observe the condition of wound healing

liquefaction of necrotic tendons

the changing of inflammatory indicators as white blood cells

CRP before and after treatment. In addition

collecting the exudation from the wound at the time of four points after wound dressing: 0

3

7

14 d. Then using them as pathological smears and testing tumor necrosis factor-α (TNF-α) and interleukin-6(IL-6) to observe the effect in diabetic wound healing by different wound dressing method

and analyze afterwards. Result: The necrotic tendons of Huafu Zaisheng group were liquefied clearer than the other two groups; the white blood cells and CRP of the three groups are declining

and the Huafu Zaisheng group is the smallest

the difference is of significance in statistics science(P＜0.05); the pathological smear of secretions shows that inflammatory cells in Huafu Zaisheng group and Huafu group significantly reduced comparing with Zaisheng group; the TNF-α in exudation of the three groups are rising

and the Huafu Zaisheng group is the highest

the difference is of significance in statistics science(P＜0.05); the IL-6 in exudation of the three groups rise first and then decreased

while the IL-6 in exudation of Huafu Zaisheng group rising and decreasing quicker than the other groups

the difference is of significance in statistics science(P＜0.05). Conclusion: Using the wound dressing method of Huafu Zaisheng

the necrotic tendons and tissues could be liquefied as early as possible

then promote the wound healing

the mechanism of which may correlated with the combination of bromelain and Shengji Xiangpigao could make the drainage unobstructed

then activate and enhance the anti-inflammatory immune mechanism of the organism

thus fits intocontrol diabetic foot infection

and promote wound healing.