Objective: To study the anti-cancer effection of Xinjiang Jujube. Method: ICR mice were randomly divided into model group

cyclophosphamide(CTX) group

25% jujube juice group

50% jujube juice group

100% jujube juice group

CTX+100% jujube juice group (n=10). Right forelimb axillary subcutaneous inoculation of S180 mouse sarcoma cells 24 h after administration (jujube juice orally 20 mL·kg-1·d-1

CTX intraperitoneal injection of 50 mg·kg-1·d-1) 14 d after the determination of tumor weight inhibition rate

index of thymus and spleen

organs

peripheral blood

serum interleukin-2(IL-2) and tumor necrosis factor-alpha(TNF-α)

the survival time and life prolongation rate. Result: Compared with model group

the CTX group

100% jujube juice group and the CTX+100% jujube juice group tumor weight

thymus

spleen index was significantly reduced; compared with the CTX group

50% jujube juice group

100% jujube juice group and the CTX+100% jujube juice group

thymus

spleen index was significantly increased; compared with model group

White blood cell count(WBC)

platelet count(PLT)

the CTX group decreased significantly

100% jujube juice group

RBC and WBC significantly increased; compared with the CTX group

50%group of jujube juice

jujube juice group of 100% and CTX+100% jujube juice group

WBC and PLT was significantly increased; compared with model group

the CTX group of IL-2 and TNF-α levels decreased significantly; compared with the CTX group.50% jujube juice group

100% jujube juice group and CTX+100% jujube juice group IL-2 and TNF-α significantly increased; compared with model group

50% jujube juice group

100% jujube juice group and CTX+100% jujube juice group significantly prolonged the survival time; compared with the CTX group

CTX+100% jujube juice group significantly prolonged survival time. Conclusion: Xinjiang jujube can significantly inhibit the growth of tumor cells in the mice.