Objective: To compare purification effect of saponins from Ziziphus jujube with different types of macroporous adsorption resin

and to optimize its purification technology. Method: With jujuboside A as index

the content of it was determined by HPLC-ELSD.Types of macroporous resin were optimized by static adsorption and dynamic adsorption method

purification technology of it was investigated by orthogonal test and single factors test. Result: For jujuboside A

there was a good linear relationship in the range of 0.216-2.16 μg

average recovery was 95.77%

RSD was 0.71%. ADS-7 macroporous resin could effectively remove pigment with better purification effect of total saponins than other resins

optimum technological parameters were:column height-diameter ratio of 3∶1

the concentration of liquid 1.0 g·mL-1

absorption velocity 1.0 BV·h-1

resin adsorption quantity 0.4 g·g-1

elution solvent 70% ethanol

elution speed 2 BV·h-1

elution solvent volume 4 BV. Conclusion: ADS-7 macroporous resin had a good purification effect on jujuboside A

optimized technology was stable

feasible

it could be used for industrial production.