This article mainly expounds the common solubilization polysorbate 80 (Tween 80﹚in the adaptability in Chinese medicine liquid formulation. Polysorbate 80's increase soluble object

quality and standard etc were discussed. Polysorbate 80 is widely used as a solubilizer

emulsifier and stabilizer in the liquid formulations of traditional Chinese medicine for decades. In recent years

people put more attention on the quality of pharmaceutical excipients and their safety because injection has a serious security problem. Because of its wide application in its production processes

product quality and safety research in vitro of tween 80 in the injection become the focus. More studies are needed on Chinese medicine liquid formulation and the safety problems of tween 80 in production and application.