To summarize the research process of universal herbal pair containing aconitine in recent years

including clinical application

chemical research

pharmacological and toxicological research

apply theoretical bases of the aconite root species safely and effectively used in clinical application. Literatures on universal herbal pair containing aconitine in recent years were summarized and analyzed. Suitable compatibility of Aconitine root species can decrease toxicity and increase efficacy

enlarge applied range. There are some advancements in studies on reducing the toxicity and increasing efficacy of aconitine by using compatibility at present

but many researches are superficial

so it is necessary for us to further study the mechanism of detoxification and synergism by using compatibility

in order to apply theoretical bases of clinical application.