Objective: To investigate the changes in the components of erythrocyte membrane proteins of the senile coronary heart disease patients with qi deficiency and blood stasis. Method: Eighteen coronary heart disease patients with Qi deficiency and blood stasis

thirteen healthy old people and ten healthy young people were the coronary patient group and healthy old people control group and healthy young people control group. The composition of erythrocyte membrane proteins was analysed by SDS-PAGE. Result: The percentage composition of band 1 protein

band 3 protein

band 4.1 protein

band 4.2 protein

band 5 protein

band 6 protein and tropomodulin of coronary patients were significantly lower than those of the healthy young people. The percentage composition of band 1 protein

band 3 protein and band 4.2 protein of the healthy old people were significantly higher than those of coronary patients. Conclusion: The mechanism of decreasing antioxidant ability and membrane fluidity may be related with the changes in composition of membrane protein.