DU Yan, ZHAO Li-jie, LI Xiao-hai, et al. Preliminary Study on Direct Compression Characteristics of Powder[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(12): 44-47.
DU Yan, ZHAO Li-jie, LI Xiao-hai, et al. Preliminary Study on Direct Compression Characteristics of Powder[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(12): 44-47.DOI:
Objective: To preliminary study on mobility and compression characteristics of D opposita powder and direct compression accessories. Method: Mobility of D. opposita powder and direct compression accessories were described by powder comprehensive characteristic test
compression characteristics of D. opposita powder was described by compression process and mechanical properties
at the same time
mathematical model method was used to evaluate and analyze compression process. Result: The compressability of Dioscorea opposita powder is poor. Though the compression characteristics of the two have similarities in Kawkita equation
they have greater differences in a great deal of respects in porosity-pressure relationship and Heckel equation. So the evaluations need comprehensive analysis and test. Conclusion: Related parameter of powder characteristics or mathematical model could be characterized features of Chinese medicine powder and direct compression excipient
however
relationship or regularity between physical properties and compression formability of drug powder were still need to be clarified.