Objective: To study the rationality for compatibility of Kushen and Baituling. Method: Four mouse models of tumor

pain

hemorrhage and inflammation were used to evaluate the pharmacodynamic effects of Compound Kushen injection (15.75

3.75 g·kg-1)

Kushen injection (10.5

5.25

2.63 g·kg-1)and Baituling injection (4.5

2.25

1.13 g·kg-1). Result : Compound Kushen injection and Kushen injection showed significant anti-tumor effect (high and middle doses)

analgesia (high and middle doses)

anti-inflammation (high dose)and hemostasis (high dose) effects. Baituling injection showed effects on analgesia (high and middle doses) and hemostasis (high dose). Compound Kushen injection could enhance the anti-tumor effect and anti-inflammation (three doses) of Kushen

promote the action of analgesia for strengthen and duration

shorten the coagulation time and hemorrhage time (high dose). Conclusion : Kushen and Baituling have synergistic action with compatible rationality in Compound Kushen injection.