Objective: To optimize extraction technology parameters of sauchinone from Saururus chinensis. Method: With the content of sauchinone as index

it was determined by HPLC. Optimum extraction technology was optimized by orthogonal test with grinding degree

the concentration of ethanol

ratio of solid-liquid

extraction time and soaking times as factors. Result: Optimum extraction conditions were:drugs passed 10 mesh sieve

extracted 2 times with 95% ethanol

14 times the amount of 95% ethanol was added for extracting 2 hours firstly

extracted 1 h with 10 times the amount of 95% ethanol in second time.In this conditions

average extraction yield of sauchinone was 0.21%

extraction transfer ratio was 96%. Conclusion: Optimized extraction technology was stable

reasonable and could be used for extraction of sauchinone from S. chinensis.