To observe the relationship between the blood stasis syndrome(BSS) defined by Chinese medicine with carotid hemodynamics

carotid atherosclerotic plaques(CAP) and atherosclerotic relative active substances. Two hundred and nine patients were selected from 306th Hospital of The Chinese People's Liberation Army.All subjects comprised 136 patients with acute cerebral infarction(CI) and 73 volunteers without acute cerebral infarction. All patients were examined with color dopplor ultrasound for hemodynamics

IMT and CAP of carotid artery. Morever

ELISA method was used to test the levels of matrix metalloproteinase-9(MMPS-9)

tissue inhibitor of matrix metalloproteinase-1(TIMP-1)

b-fibroblast growth factor(b-FGF)

high sensitive C-reactive protein(Hs-CRP) and blood-lipid in blood-serum in CI patients. The patients with BSS had AS. There was correlation between carotid diameter

the number of CAP and ulcerative CAP with BSS.Morever

the CAP in patients with BSS have unstablity. The number and unstablity of CAP increased in patients with BSS have CI. The carotid diameter of patients with BSS increased

and also the patients with BSS had CAS and abnormal carotid hemodynamics. The carotid diameter

the degree of CAS and number of CAS increased in paitents with BSS have CI. There was correlation between matrix metallopeptidase-9(MMP-9) with BSS. Contrarily

there was no correlation between TIMP-1

b-FGF

Hs-CRP

blood-lipid with BSS. Conclusion: The important pathological basis of blood stasis syndrome(BSS) defined by Chinese medicine is Atherosclerosis.