Objective: This article is to analyse the compatible rules and the mechanism of the clinical application between Dioscoreae Rhizoma and Poria

which could offer some suggestions to highlight the importance of compatibility of medicines in clinics. Method: Dioscoreae Rhizoma and Poria are both traditional Chinese medicine in common clinical use. Based on the compatible mechanism

combination character and the modern relative research

we collect and record the formulae containing Dioscoreae Rhizoma from the classic format Formula Dictionary of Traditional Chinese Medicine into Excel.Then we have an analysis of the compatible mechanism and the clinical sense of Dioscoreae Rhizoma and Poria. Result: The kind of traditonal Chinese drugs of highest frequency combined with Dioscorea opposita Thunb. is tonic drug. The traditonal Chinese drug of highest frequency combined with Dioscorea opposita Thunb. is Poria cocos(Schw.)wolf. Conclusion: The combination of Dioscoreae Rhizoma and Poria has wider use in clinics through reinforcing and reducing methods

which is the reference of more value for the clinics and health protection.