Objective: To evaluate the effect of Sanzi Pingchuan granule on treating children with asthmatic respiratory tract infection. Method: Fifty cases of asthmatic respiratory tract infection in children were randomly divided into control group and treatment group (25 cases each). Control group was given conventional western treatment (antibiotics

antivirotic

aerosol inhalation

corticosteroids and necessary supportive therapy). Treatment group was given Sanzi Pingchuan granule on the basis of western treatment. Both groups were treated for seven days as a course

then to evaluate the clinical efficacy. Result: Both groups showed significant effect after treatment compared to before

respectively. Although there were no significant differences in the degree of improvement in cough

sputum

pulmonary wheezing sound and coarse rales

composite score and the total effective rate between control group and treatment group

treatment group significantly alleviated wheezing and panting symptom on fifth and seventh day compared with control group(0.28±0.84 vs 0.92±0.57

0.08±0.28 vs 0.32±0.56

respectively

P<0.05). Conclusion: Sanzi Pingchuan granule combined with western treatment for treating children with asthmatic respiratory tract infection appears to be significantly effective on alleviating wheezing and panting compared with western treatment alone. The therapeutic approach might be widely applied.