ZHANG Xiao-mei. Combination of Shenmai Injection with Leucogen Tablets for Treatment of Leucopenia after Chemotherapy[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(13): 282-284.
ZHANG Xiao-mei. Combination of Shenmai Injection with Leucogen Tablets for Treatment of Leucopenia after Chemotherapy[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(13): 282-284.DOI:
Objective: To observe the clinical efficacy of the joint Shenmai injection with Leucogen tablets for leukopenia after chemotherapy. Method: Sixty patients were randomly divided into observation group and control group(n=30 each). Two groups were given Leucogen tablets
vitamin C tablets
vitamin B tablets in the treatment
while giving the observation group Shenmai injection. Two groups are treated for 4 weeks for a course
a clinical effect observed after treatment and changes in white blood cells. Result: The observation group was 36.67% significant efficiency
the control group was 20.00%
comparison showed significant difference (P<0.05); the total effective rate was 76.67% in the observation group
66.67% in the control group(P<0.05). In both groups
the white blood cell count after the first week of treatment was rapidly reduced
compared with before treatment (P<0.05). Two weeks after treatment
white blood cell count in two groups continued to decline
with significant difference before treatment (P<0.05); 3 weeks after treatment had rebounded. The white blood cell count was(3.58±0.4)×109/L in the observation group and (2.82±0.6)×109/L in the controls after 3 weeks treatment (P<0.05);and (4.58±0.85)×109/L and (3.20±0.74)×109/L after 4 weeks treatment accordingly(P<0.05). Conclusion: Shenmai injection with Leucogen tablets for leukopenia after chemotherapy is effective.