JIA Yong-yan, ZHU Xia-li, CHEN Bo, et al. Optimization of Purification Process for Chitosan from Fengbingkang Mixture by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(11): 32-34.
JIA Yong-yan, ZHU Xia-li, CHEN Bo, et al. Optimization of Purification Process for Chitosan from Fengbingkang Mixture by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(11): 32-34.DOI:
Objective: To investigate purification technology of Fengbingkang mixture with chitosan as clarification agent. Method: With the content of baicalin from purified liquid as index
flocculation clarification process was optimized by orthogonal design
and compared with traditional ethanol precipitation process. Result: These test result showed that optimized technology was better than ethanol precipitation technology.Optimum flocculation clarification process conditions were:water extraction liquid concentrated to 1 : 8
the amount of chitosan 15%
temperature 50 ℃. Conclusion: Chitosan clarifying agent could be used for purifying Fengbingkang mixture.