ZHOU Qin-mei, ZHANG Yuan, CHEN Wu. Application of Quantitative Characteristic Spectrum to Quality Evaluation of Buyanghuanwutang[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(14): 75-78.
ZHOU Qin-mei, ZHANG Yuan, CHEN Wu. Application of Quantitative Characteristic Spectrum to Quality Evaluation of Buyanghuanwutang[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(14): 75-78.DOI:
Objective: To evaluate the quantitative characteristic spectrum to control the quality of buyanghwanwutang the product by extent. Method: The Characteristic spectrum of buyanghuanwutang was established. In methodological study
peoniflorin as the reference peak to calculate the RSD of the relative retention time and relative peak area of each common peaks
precision
stability and reproducibility were investigated as well. The characteristic spectrums of 10 batches of buyanghuanwutang were established.The quality of buyanghuanwutang was evaluated by the correlation
cosine of the angle and extent similarity of ten batches
combined with the numericalsimilarity. Result: RSD of the relative retention time and relative peak area of common peaks of precision
accuracy
repeatability was less than 3%.The calculation results of Samples' correlation coefficient and angle cosine are above 0.95
it cannot reflect the differences among samples
but there is a great difference in extent similarity
so it can reflect the differences among samples. The combination of the extent similarity and numerical similarity was better than the correlation
cosine of the angle. The combination reflected the differences of different batches
and was used to control the quality of products. Conclusion: This method is accurate and reliable
for quality evaluation of Traditional Chinese Medicine.