Objective: To study the effects of Naomai Shukang capsule on energy metabolism in rat blood stasis with cerebral ischemia models. Method: Blood stasis model was replicated with injection of dexamethasone. Model rats were administrated orally with Naomai Shukang capsule according to dosages of 0.9

0.6

0.3 g·kg-1 for 10 d. After the rats were administrated with drugs for 1 h on the 11th day

Cerebral ischemia models were made by ligating both sides of the common carotid arteries of rats for 30 min. Na+-K+-ATPase

Mg2+-ATPase

Ca 2+-ATPase activity

lactic acid(LD) content and lactate dehy drogenase(LDH) activity of brain homogenates were measured. Result: Three doses of Naomai Shukang capsule can improve the ATP activities(P<0.01 or P<0.05). The high and medium dose can reduce the LD content(P<0.01). The medium and low dose can increase the LDH activity(P<0.01). Conclusion: Naomai Shukang capsule can improve brain energy metabolism in rat blood stasis with cerebral ischemia models and reduce lactic acid accumulation and damage to brain tissue.