Objective: To screen the effective parts from Erchen Tang for expectorant and antitussive. Method: The mice were allotted into 12 groups as following: physiogical saline

DHS group

the five part from Erchen decocotion groups with high dose(HD) and low dose(LD

15

3.75 g·kg-1)

the mice were orally administered for 3 days

the antitussive effect was observed by concentrated ammonia method after 1 h. The mice were allotted into 12 groups as following: physiogical saline

AHOS group

the five part fron Erchen decocotion groups with high dose(HD) and low dose(LD

15

3.75 g·kg-1)

the mice were orally administered for 3 days

the expectorant effect was observed by increased the secretion of expect oration method after 30 min. The cavies were allotted into 12 groups as following: physiogical saline aminophylline group

the five part from Erchen decoction groups with high dose(HD) and low dose(LD

8.32

2.08 g·kg-1)

the cavies were orally administered for 3 days

the antiasthmatic effect was observed by spray method after 1 h. Result: Essential oil

butanol and water fractions could reduce the frequency of cough

and increase secretion of expectoration

and inhibitory asthma(P＜0.01

P＜0.05);petroleum ether and ethyl acetate fractions could not reduce the frequency of cough

could not increase secretion of expectoration

and inhibitory asthma. Conclusion: The results show that petroleum ether and ethyl acetate fractions were invalid

essential oil

butanol and water fractions were the effective parts of Erchen Tang for expectorant and antitussive.