Objective: To study the pharmacology effect of different polar extracts from Aucklandia lappa and its processed products. Method: The stomach mucous membrane injury model induced by hydrochloric acid-alcohol was adopted. SD rats were divided randomly into control group

model group

A. lappa group(2

6 g·kg-1)

processed products of A. lappa group(2

6 g·kg-1)

volatile oil group from A. lappa (2

6 g·kg-1)

volatile oil of processed products from A. lappa group(2

6 g·kg-1)

the gastric percentage was calculated. Result: The essential oil of processed products from A. lappa and A. lappa (2

6 g·kg-1)significantly inhibited the injuries of gastrointestinal mucous membrane(P<0.01)

and the activity of essential oil of processed products of A. lappa (6 g·kg-1) was stronger than A. lappa (6 g·kg-1). However

the influence of A. lappa on rats’ gastrin was not remarkable

only essential oil of A. lappa (2g·kg-1) exhibited enhance of rats’ gastrin. Conclusion: The essential oil of A. lappa may hence the inhibition effect on injuriy of stomach mucous membrane.