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纸质出版日期:2012
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杨宇峰, 石岩. 并有糖调节受损的代谢综合征中医辨证分型风险因素临床研究[J]. 中国实验方剂学杂志, 2012,18(6):257-259.
YANG Yu-feng, SHI Yan. Clinical Study on Chinese Medicine Syndrome Patterns and Risk factors in MS Combined IGR[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(6): 257-259.
目的: 观察并有糖调节受损(IGR)的代谢综合征(MS)中医痰热互结证和气阴两虚证型相关危险因素。 方法: 通过"十一五"国家科技支撑计划中医药项目调查的北京、山东、辽宁等地符合西医及中医证型诊断的并有IGR的MS 353例患者
收集年龄、性别、体重指数(body mass index
BMI)、腰围(waist cincumference
WC)、收缩压(systolic blood pressure
SBP)、舒张压(diastolic blood pressure
DBP)、总胆固醇(total cholesterol
TC)、甘油三酯(triglyceride
TG)、高密度脂蛋白(high density lipoprotein
HDL)、低密度脂蛋白(low density lipoprotein
LDL)、空腹血糖(fasting plasma glucose
FPG)、餐后2 h血糖(2 hours plasma glucose
postprandial blood glucose;2 hPG
PBG)、糖化血红蛋白(HbA1c)等主要指标进行分析。 结果: ①痰热互结证型患者BMI
WC高于气阴两虚组(P<0.05);②痰热互结证的PBG高于气阴两虚组(P<0.05);③血压与并有IGR的MS中医辨证分型无相关性;④痰热互结证的LDL高于气阴两虚组(P<0.05)。 结论: BMI
WC
PBG
LDL是并有IGR的MS痰热互结证的危险因素
临床治疗中要重视化痰清热法。
Objective: To observe syndrome patterns of chinese medicine and risk factors in metabolic syndrome(MS) complicated impaired glucose regulation(IGR) with combination of phlegm and heat and deficiency of both Qi and Yin. Method: The clinical study was conducted in 353 patients with MS complacated IGR from Beijing
Shandong and Liaoning province. The following indexes were observed
including body mass index(BMI)
waist cincumference(WC)
systolic blood pressure(SBP)
diastolic blood pressure(DBP)
total cholesterol(TC)
triglyceride(TG)
high density lipoprotein(HDL)
low density lipoprotein(LDL)
fasting plasma glucose(FPG)
postprandial blood glucose(PBG)
glycolated hemoglobin(HbAlc) Result: ①BMI and WC in combination of phlegm-heat group were higher thandeficiency Qi and Yin group(P<0.05).②PBG in combination of phlegm-heat group group was higher than deficiency of Qi and Yin group(P<0.05).③No correlation was found in chinese medicine syndrome patterns. ④LDL in combination of phlegm-heat group was higher than deficiency of Qi and Yin group(P<0.05). Conclusion: BMI
WC
PBG and LDL are risk factors in combination of phlegm-heat group
attention should be payed to treatment of combination phlegm-heat syndroms in clinical.
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