To evaluate objectively the clinical curative effect of the therapy of dissipating phlegm and removing blood stasis for vascular cognitive impairment(VCI)with Meta-analysis. According to the method of Cochrane Systematic Review

CBM

CNKI

VIP

Wanfang (2001-2011)

etc were searched. Randomized controlled trials of treatment by dissipating phlegm and removing blood stasis for vascular cognitive impairment were collected for systematic reviews

extract data and Meta-analysis were analysed with Revman 5.0. A total of 13 trials were included in this study

including 944 cases patients. Those trials were low quality

the results showed that: ①the therapy of dissipating phlegm and removing blood stasis had a better efficacy than the control group by mini-metal state examination(MMSE)

Hamton Depression Scale(HDS)

Scale for the differentiation of vascular dementia(SDSVD)(P<0.05)

②there was no significant difference shown by Berg Balance Scale(BBS)

③the therapy had a good safety. Available evidences manifests that dissipating phlegm and removing blood stasis has a better efficacy and safety than the control group

but less attention is paid to clinical symptoms. Due to lower overall quality and potential publication bias of the studies. The rational design

the strict execution

the multi-central and large sampling

long time follow-up and double-blind randomized controlled trials with characteristics of Chinese medicine are needed in the future.