Objective: To establish the quality control standard of Qichan Koufu Jiechang Baxiang tablets. Method: Astragalus

corium bufon and flavescens were identified by TLC. The UPLC and HPLC in preparations for astragaloside Ⅳ

resibufogenin and cinobufagin

matrine are quantificationally analyzed. Result: The characteristic for identification by TLC was distinct and highly specific. The linear range of astragaloside Ⅳ was 0.233 6-0.817 6 μg(r=0.999 9)

and the average recovery was 99.66%(RSD 1.14%). The linear range of resibufogenin concentration was 0.001 75-0.010 5 μg(r=1.000 0)

and the average recovery was 100.44%(RSD 1.94%). The linear range of cinobufagin concentration was 0.003 51-0.021 06 μg(r=1.000 0)

and the average recovery was 99.57%(RSD 2.73%). The linear range of Matrine concentration was 0.336 8-1.178 8 μg(r=0.999 8)

and the average recovery was 100.30%(RSD 1.11%). Conclusion: The detection method is simple

reliable

reproducible and can be suitable for quality control of Qichan Koufu Jiechang Baxiang Tablets.