LI Ya-zhou, GAO Chong, HU Xiao-cheng, et al. Syudy on Effects of Alcohol Extract of Fruits on Secondary Dysmenorrhea Induced by Endometritis[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(3): 153-155.
LI Ya-zhou, GAO Chong, HU Xiao-cheng, et al. Syudy on Effects of Alcohol Extract of Fruits on Secondary Dysmenorrhea Induced by Endometritis[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(3): 153-155.DOI:
1.2 g ·kg-1剂量组大鼠的子宫肿胀度、血浆黏度、红细胞聚集率均显著低于模型组(P<0.01或P<0.05);1.2 g ·kg-1剂量组大鼠全血黏度显著低于模型组(P<0.01);0.6
1.2 g ·kg-1剂量组大鼠子宫组织中的PGE2含量显著低于模型组(P<0.05)。结论: AETF治疗子宫内膜炎继发性痛经的作用与血液流变学指标的改善、子宫组织中PGE2含量的降低有关。
Abstract
Objective: To observe the effects of the alcohol extract of Thladiantha dudia fruits (AETF) on secondary dysmenorrhea induced by endometritis. Method: The secondary dysmenorrhea model of endometritis was established by implanting the plastic tube into uterus. Degree of uterus edema
hemorheology(blood viscosity
blood plasma viscosity
erythrocytes aggregation)and concentration of prostaglandin E2 (PGE2) were observed. Result: AETF 0.3
0.6
1.2 g ·kg-1groups clearly decreased blood plasma viscosity and erythrocytes aggregation
depressed degree of uterus edema
as compared with model group (P<0.01 or P<0.05). AETF 1.2 g ·kg-1group clearly decreased blood viscosity
compared with model group (P<0.01 or P<0.05). AETF 0.6
1.2 g ·kg-1groups clearly decreased concentration of PGE2 in the uterus
compared with model group (P<0.05). Conclusion: The effects of AETF on secondary dysmenorrhea induced by endometritis are related to amelioration of hemorheology and reduction of PGE2 concentration.