Objective: To study the experimental antipyretic and antiemetic effects of the powder of Baoji Wan before and after irradiation. Method: Rat fever model was established by yeast to observe the antipyretic effect of the powder of Baoji Wan before and after irradiation. Pigeon vomiting model was induced by using copper sulfate to investigate the antiemetic effect of the powder of Baoji Wan before and after irradiation. Result: The powder of Baoji Wan could significantly reduce the temperature of yeast-induced fever in rats before and after irradiation

compared with the control group (P<0.01 and P<0.05). The powder of Baoji Wan could significantly reduce the number of copper sulfate-induced vomiting in pigeons

compared with the control group (P<0.05). Conclusion: The powder of Baoji Wan has antipyretic and antiemetic effects before and after irradiation. The effect's comparison for before and after irradiation

the difference was not significant.