Objective: To establish quality standards for Mayi Rhinitis Spray. Method: The content of ephedrine hydrochloride and berberine hydrochloride in the Mayi Rhinitis Spray was determined by HPLC

and the qualitative analysis for Herba Ephedrae

Flos Magnoliae

Cortex Phellodendri were performed using TLC. Result: There was good linearity for ephedrine hydrochloride within the range of 7-35 mg·L-1 (r=0.999 9)

and its average recovery was 98.64% with RSD at 1.69% (n=9). There was good linearity for berberine hydrochloride within the range of 1.4-70 mg·L-1 (r=0.999 7)

and its average recovery was 98.30% with RSD at 1.84% (n=6). Herba Ephedrae

Flos Magnoliae

Cortex Phellodendri could be accurately identified by TLC. Conclusion The method is simple

rapid and reproducible

and it can be used for the quality control of Mayi Rhinitis Spray.