WANG Kun, ZHANG Zhen-ling, JIA Xiu-mei. Optimization of Extraction Technology of with Multi-components Quantitation by One Marker[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 9-11.
WANG Kun, ZHANG Zhen-ling, JIA Xiu-mei. Optimization of Extraction Technology of with Multi-components Quantitation by One Marker[J]. Chinese journal of experimental traditional medical formulae, 2011, 17(24): 9-11.DOI:
Objective :To optimize extraction technology of Coptis chinensis. Method :Determined the content of epiberberine
coptisine
berberine and palmatine with multi-components quantitation by one marker
orthogonal design was used to optimize extraction technology of C. chinensis with total content of epiberberine
coptisine
berberine and palmatine. Result :The best extracting condition was as follows:extracted 3 times with 10 times the amount of 70% ethanol for 1.5 h each time. Conclusion : Optimum extraction technology was effective for extracting multiphasic alkaloid from C. chinensis.