Objective: Cancerous pain is one of the most frequently appeared symptoms. It is also the common

early and painful symptom in patients with osseous metastasis. In recent years

by combination of syndrome differentiation and disease differentiation

and by the combination of traditional internal therapy with external therapy

there are significant progresses in the clinical research on treatment of cancerous pain induced by malignant metastasis. Some of the therapeutic approaches have gained satisfactory efficacy

with advantages of treating both the principal and the secondary aspects of a disease

less side effects and lower cost. Clinical research emphasizes multi-centered

randomized

double blind

sufficient large sampling

reasonably established control group

standardized evaluation criteria for cancerous pain. Meanwhile

attentions should be paid to the evaluation parameters for clinical benefits

the quality control of medicinal preparations

and the research on the effective components responsible for the efficacy. These issues are goals and the problems should be reached and solved in the near future.