Objective: To compare effect of different extraction methods to extraction efficiency of polysaccharide from Caulis Polygoni Multiflori. Method: The content of polysaccharide was determined by phenol-sulfuric acid method

study on different extraction methods for polysaccharide from Caulis Polygoni Multiflori with the content and yield of polysaccharide as indexes. Result: Sodiumhydroxide extraction method was the best by comparing with other five methods

yield and the content of polysaccharide were up to 25.13%

21.46%

respectively. Conclusion: Sodiumhydroxide extraction was proved to be a high efficiency and stable method for extraction of polysaccharide from Caulis Polygoni Multiflori.