ZHANG Jun, LIU Yu-zheng, WANG Yue-sheng, et al. Optimization of Extraction Technology for Gegen Qinlian Decoction with Multi-index Comprehensive Evaluation Method[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(2): 1-3.
ZHANG Jun, LIU Yu-zheng, WANG Yue-sheng, et al. Optimization of Extraction Technology for Gegen Qinlian Decoction with Multi-index Comprehensive Evaluation Method[J]. Chinese journal of experimental traditional medical formulae, 2012, 18(2): 1-3.DOI:
Objective: To establish the optimal extraction technology of Gegen Qinlian decoction. Method: A HPLC method was established to simultaneously determine 12 active ingredients in the extractions of Gegen Qinlian decoction. Based on the orthogonal design of L9(34) and the weighted method
three factors including the multiple water
decocting time
and extracting times were evaluated. Result: Significant effect was observed in extracting times. The optimal extraction technology was 8 times volume of water extracting 3 times with 1 h for each time. Conclusion: The extraction technology optimized with multi-index comprehensive evaluation method is reasonably practicable. It could be used in future large-scaled preparation of Gegen Qinlian decoction.