Objective: To compare extraction effect of scutellarin from Yandeng dripping pill by different extraction methods. Method: With the content of scutellarin and yield of extract as indexes

optimum extraction technology of ethanol refluxing

ultrasonic extraction and flash extraction were investigated by L16(45) orthogonal test

U10(106)and U4(54)uniform-designed experiments

respectively.And compared extraction capability of scutellarin from Yandeng dripping pill. Result: The average contents of scutellarin with ethanol refluxing method

ultrasonic extraction method

flash extraction were 3.26%

2.61%

2.15%;And average extraction ratio were 26.23%

14.02%

19.2%. Conclusion: The content of scutellarin and extraction ratio was the best by ethanol refluxing

it provided theoretical basis for extraction method of Yandeng dripping pill.